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Abstract
Early Tamils and Dravidians in South India are thought to have used siddha, one of India's oldest medical systems, as their primary treatment. It is the most ancient system and has many specialties that are superior to those of Ayurvedic medicine. The plant, widely recognized as Gotu Kola, Asiatic pennywort, Indian pennywort, or Spadeleaf, is a member of the Umbelliferae/Apiaceae family. It has been cultivated as a vegetable in regions such as China, Southeast Asia, India, Sri Lanka, Oceania, and Africa for centuries. In Southeast Asia, it has a traditional role in treating various ailments, including skin conditions, rheumatism, inflammation, syphilis, mental health issues, epilepsy, hysteria, dehydration, and diarrhea. In Indian medicinal practices, Centella asiatica (Gotu Kola) is valued for its memory-enhancing properties and its effectiveness in addressing skin disorders and nervous system issues. The medicinal benefits of this plant have been recognized by the inhabitants of Java and Indonesia for a long time. In China, it is referred to as Gotu Kola, and it was documented over 2000 years ago as one of the "miracle elixirs of life."The initial phytochemical analysis of the ethanolic extract of Centella asiatica revealed the presence of several phytochemical constituents, including carbohydrates, phenols, flavonoids, steroids, alkaloids, glycosides, proteins, tannins, terpenes, and saponins. However, sterols, gums, and mucilage were not detected.It can be concluded that Centella asiatica exhibits notable anti-epileptic effects in both MES and INH induced epilepsy in Wistar rats, comparable to the effects of Phenytoin and Diazepam. Additional research is required to clarify the mechanisms underlying the antiepileptic effects of Centella asiatica, particularly concerning its phytochemical components.