The Effect of Centella Asiatica for Wound Healing

Abstract

Centella asiatica is a perennial creeper with a faint aroma and is a valuable medicinal herb in both the Old and New Worlds. It is found in tropical and subtropical regions around the world, including India, China, Nepal, Madagascar, Sri Lanka, and Indonesia. Centella's popularity in food and beverages stem from its functional properties. The plant's bioactive constituents have been linked to potential antioxidant, antimicrobial, cytotoxic, and neuroprotective activities, as reported in numerous studies. The plant's chemistry and pharmacology have been extensively studied for its efficacy in herbal preparations and chemical isolates, both ancient and modern. An intense effort has been made to develop new therapeutic approaches as well as technologies for more efficient and rapid wound healing. Research into plants that have long been used in traditional medicine to treat wounds has become a promising strategy for obtaining drugs that are therapeutically useful in acute and chronic wound management. Centella asiatica (Apiaceae) extracts and their active constituent, asiaticoside, have been shown to promote wound healing in both in vivo and in vitro models. We aim to create a formulation that promotes faster wound healing. This review provides a current and comprehensive analysis of the chemistry and health benefits of the Centella plant.