Manuscript Preparation
Prepare a manuscript that allows editors, reviewers and readers to understand exactly why the study was performed, how it was conducted, what was found and what the evidence can legitimately support.
Scientific clarity, reproducibility and pharmacy relevanceRecommended order
- Title page
- Abstract and keywords
- Main text appropriate to the article type
- Acknowledgements and author-contribution statement
- Ethics, consent, trial registration, data, funding and competing-interest declarations
- References
- Tables, figure legends and supplementary-material description
Title page and author metadata
Provide a concise informative title; all author names in publication order; department, institution, city and country for each affiliation; a clearly identified corresponding author with email address; and ORCID iDs where available. Avoid unrecognised qualifications and honorary titles in the byline. A running title may be added when helpful.
Abstract and keywords
Original research should use a structured abstract such as Background, Objective, Methods, Results and Conclusion, including essential numerical results rather than general claims. Reviews should state their purpose, information sources or approach, principal findings and conclusions. Do not cite references or introduce undefined abbreviations in the abstract. Supply 3–6 specific keywords, using recognised biomedical terms where suitable.
Main text for original research
Introduction
Define the problem, summarise the relevant evidence, identify the knowledge gap and end with a clear objective or hypothesis.
Methods
Describe design, setting, dates, materials, participants or samples, groups, procedures, outcomes and statistical analysis in enough detail for evaluation and replication.
Results
Present findings in a logical order with denominators, units, effect estimates and uncertainty where applicable. Do not duplicate every value in text and tables.
Discussion
Interpret the principal findings against existing evidence, explain plausible mechanisms and practical relevance, address limitations and avoid claims beyond the data.
Pharmaceutical reporting details
- Formulation studies: identify material grades and suppliers, composition, processing parameters, controls, batch numbers, optimisation strategy, validation and stability conditions.
- Analytical studies: state instruments, reference standards, calibration, sample preparation, validation characteristics, system suitability and applicable guidance.
- Pharmacology and toxicology: report model justification, randomisation, blinding, dose rationale, route, timing, controls, humane endpoints and statistical unit.
- Pharmacokinetic studies: describe sampling, assay, model or non-compartmental methods, key parameters, below-quantification handling and bioavailability or bioequivalence criteria.
- Natural products: give accepted taxonomy, plant part, origin, collection and permit details, voucher specimen, authentication, extraction, chemical characterisation and standardisation.
- Clinical and pharmacy-practice research: define setting, population, exposure or intervention, comparator, outcomes, missing data, confounding and patient/public relevance.
Statistics
Identify the statistical software and version, prespecified analyses, sample-size rationale, assumptions, handling of missing data and multiplicity where relevant. Report exact P values when practical, together with effect sizes and confidence intervals. Distinguish technical replicates from independent experimental units. Statistical significance alone should not be presented as clinical or practical importance.
Tables, figures and images
Number each item in order of citation. Tables must be editable, self-contained and not screenshots. Figures should remain legible at publication size. State the meaning of error bars and all symbols. Changes to brightness, contrast or colour must apply to the complete image and must not obscure, eliminate or misrepresent information. Any grouping of lanes, fields or images must be visibly separated and explained. Permission is required for reused copyrighted material.
Required end matter
Use separate labelled statements for author contributions, acknowledgements, funding, competing interests, ethics approval, consent to participate, consent for publication, clinical-trial registration and data availability. Write “Not applicable” only when the item genuinely does not apply; do not omit the heading to conceal missing information.
Reporting resources
Consult the EQUATOR Network when choosing a study-design guideline. Protocols, flow diagrams and completed checklists should agree with the submitted manuscript.

